After using Pop!_OS for about a month the icons inside a GNOME folder shrank. I re-installed it and have not been able to duplicate the issue. However, now on my Fedora 33 install the same issue occurred.
In my Applications Launcher I created folders. Only in the folders with more than 9 or 10 items has this occurred, but the icons became much smaller. This is how it is in all my folders with more than 9 or 10 items. Both pictures were selected using the edge of the box the icons were located.